DISC1 Pathway in Brain Development: Exploring Therapeutic Targets for Major Psychiatric Disorders
نویسندگان
چکیده
منابع مشابه
DISC1 Pathway in Brain Development: Exploring Therapeutic Targets for Major Psychiatric Disorders
Genetic risk factors for major psychiatric disorders play key roles in neurodevelopment. Thus, exploring the molecular pathways of risk genes is important not only for understanding the molecular mechanisms underlying brain development, but also to decipher how genetic disturbances affect brain maturation and functioning relevant to major mental illnesses. During the last decade, there has been...
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Disrupted in schizophrenia 1 (DISC1) is well established as a genetic risk factor across a spectrum of psychiatric disorders, a role supported by a growing body of biological studies, making the DISC1 protein interaction network an attractive therapeutic target. By contrast, there is a relative deficit of structural information to relate to the myriad biological functions of DISC1. Here, we cri...
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ژورنال
عنوان ژورنال: Frontiers in Psychiatry
سال: 2012
ISSN: 1664-0640
DOI: 10.3389/fpsyt.2012.00025